Sentence examples for variants affecting a from inspiring English sources

Our results show that among all the sequences mapping onto miR-101, 5'-trimming variants affecting a single nucleotide position are highly abundant in human samples and show variable expression depending on the sample.

In just the last few years, GWAS have been used to identify hundreds of variants affecting a diverse range of common diseases and disease associated quantitative traits (for a summary, see http://www.genome.gov/gwastudies/).gov/gwastudies/

These variants affected a total of 963 individuals giving a genotype prevalence of 1 7 (963:6334).

These variants affected a total of 1474 individuals, which is equivalent to a HCM genotype prevalence of 1 4 (1474:5810).

In a small number of cases, multiple variants affect a single position, in which case we use the most proximal deletion and ignore any other variants overlapped by that deletion.

The effect of each point variant on kcat/ KM CTAD) was nearly identical to their effect on kcat, indicating that the variants affected a step that was separate from CTAD binding.

Recently, a study of 48 small intestine neuroendocrine tumors by parallel exome sequencing indicated that somatic single nucleotide variants affected a preponderance of cancer genes, including FGFR2, MEN1, HOOK3, EZH2, MLF1, CARD11, VHL, NONO and SMAD1[ 24].

Epistasis occurs if the effect of one variant affecting a complex trait depends on the genotype of a second variant affecting the trait.

For a variant affecting a quantitative trait, this can translate to higher variance in the trait in heterozygous than homozygous females.

For an X-linked variant affecting a quantitative trait, random X-inactivation can translate to higher variance in the trait in heterozygous females compared to homozygous females.

Subsequently, substitution of the minor for the major variant affecting a C/EBP transcription factor binding site was shown to reduce expression from a luciferase reporter gene, confirming the identity of rs12740374 as the eSNP.