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The four peptide loops that form its ligand-binding site were randomized and a cognate variant was selected from the resulting library.
Furthermore, it has also been shown that this variant was selected during rice domestication for increased yields.
Furthermore, it fails to provide a guarantee that the true causal variant is selected.
The Jmol applet is loaded automatically with an available structure model when a variant is selected on the web interface.
If multiple Affymetrix probe sets were present for the same gene, the maximum fold change variant was selected.
The rs2325934 variant was selected because it exhibited the lowest p-value of association (pint) in the discovery analysis.
The resample model inclusion probability (RMIP) was calculated for each variant as the proportion of 100 data samples in which the variant was selected in the regression model.
Where more than one SNP was associated at a particular locus with CeD, the most associated variant was selected for genotyping in the RA case-control cohort.
The variant was selected for genotyping because there was suggestive evidence for association with T1D in one large case control series (P = 5.0 ×10−6), although this was not subsequently replicated in a smaller family-based study (8).
This variant was selected because a similar SLI substrate with the natural G at this position did not form a stable homogeneous complex with SLV for NMR studies (data not shown).
The PvuII (rs2234693), XbaI (rs9340799), codon 243 (rs4986934) and codon 325 (rs1801132) variants were selected from the literature and added to our SNP selection.
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CEO of Professional Science Editing for Scientists @ prosciediting.com