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An analysis of the 14,250 people whose DNA had been mapped in 14 studies showed that those with the variant were not at greater risk of depression than those without it.
This data clearly suggested that intratumor heterogeneity (variants with low allelic fractions that are truly different between FF and FFPE tissue specimens) or sampling heterogeneity (rare variants present in the tissue specimens but missed by sequencing because the individual molecules with that variant were not sampled) were important explanations for the differences observed in SNV calling.
Of the over 700 participants in the study, none of which had dementia, the people who had one copy of the gene variant were not only more likely to live longer, they also had a decreased chance of stroke.
Arg/Arg homozygotes of the KIF6 variant were not at increased risk of MI, compared with Trp/Trp homozygotes.
Specifically, it has been shown that overweight children with a specific MC4R variant were not able to maintain their weight loss achieved during a lifestyle intervention in contrast to children without these mutations [24].
We found that carriers of one or two copies of the KIF6 719Arg variant were not at increased risk of MI (OR = 1.12; 95%CI, 0.98 1.28; Table 2).
Similar(49)
The origins of this influenza variant is not precisely known.
The R150S variant was not found in this sample set.
Therefore, we concluded that the splicing variant was not pathogenic.
But some population-specific variants may exist, and a population could fail to benefit if the variant is not detected.
The RICH diet variant is not feasible with ruminant products (Supplementary Fig. 7).
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CEO of Professional Science Editing for Scientists @ prosciediting.com