Your English writing platform
Discover LudwigSuggestions(1)
Exact(4)
However, this model does not require a constitutively active Ras variant to induce glioma formation.
This is consistent with the comparable ability of wtBMP2 and heteromeric wtBMP2/L51P variant to induce ALP, in that at variant concentrations required for half-maximal ALP induction (10 to 20 nM) pSMAD-1 levels are similarly high.
The diminished ability of the 196R variant to induce NF-κB activation is paralleled by a diminished induction of NF-κB dependent target genes involved in antiapoptotic or proinflammatory functions.
It is possible that in certain cell types or under particular experimental conditions that the reduced ability of the 196R variant to induce NF-κB dependent genes may lead to reduced release of sTNFRs (e.g. through lower production of proteins that are important in regulating the cleavage and release of these receptors).
Similar(56)
We further investigated the potential of the 2 variants to induce proinflammatory responses in human cells.
The homodimeric coreBMP2L51P variant fails to induce ALP expression, which is in agreement with results published earlier using similar BMP variants that have both type I receptor sites destroyed [ 33, 40].
Only those cells expressing the P5L variant appeared to induce the expression of type X collagen [ 31].
In contrast, the C-terminally truncated variant was unable to induce β-casein/luciferase activity upon prolactin stimulation in vitro.
For the variant to be induced by EMS, we computed the GQ for the plant yielding the change which is based on the likelihood of a particular genotype being called in comparison to the likelihood of the other two genotypes being called: L(0/1) versus L 0,0) and L 1,1).
When co-incubated with Aβ, some Aβ linker variants were found to induce accumulation of Aβ oligomers.
Dominant-negative Ush variants are able to induce lamellocyte differentiation and it has been suggested that Ush regulates lamellocyte differentiation from a potential plasmatocyte [22].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com