A common genetic variant that produces a weakened version of the enzyme increases risk of birth defects and possibly of heart disease, although it's not clear why.
We identify a ZIKV variant that produces small plaques due to interferon (IFN -restricted vIFN -restrictedn and displays attenuated infection of endothelial cells.
If people have a genetic variant that produces a different form of this bitter receptor, however, they are deaf to this back-channel bacterial chatter, and are more prone to severe sinus infections.
§ epf*, an epf variant that produces an ≈3,000-bp ≈3,000-bpby PCR with primers described previously (10 ); mrp** and mrpS, mrp variants that produce ≈1,800-bp and ≈750-bp fragments, respectively, by PCR with primers described previously (10 ).
The point mutant ADAR1 G1007R is an unusual example of a DSH1-associated variant that produces a full-length ADAR1 protein.
There are two variants, an altruistic variant that produces a benefit to all group members and a selfish variant that does not.
Two other groups have described mice with related hypo-morphic mutant Brca1 alleles that remove all or part of exon 11 while preserving the Δ11 exon splice variant that produces a truncated Brca1 protein.
False discovery rates for eQTL were conditioned by the likelihood that traits would map near Comt based on a target interval of 4 Mb and the relative density of sequence variants that produce eQTLs.
† mrps and mrp* are mrp variants that produce ≈750-bp and ≈1,800-bp ≈1,800-bp, respectively, by PCR (23, 34 ).
Genetic variants that produce gene-environment interactions may only do so when the exposure corresponds to a critical developmental window during which that gene is highly expressed.
