Alternatively some or all signals may each be correlated with the same variant that has been neither genotyped nor imputed.
Through luck rather than virtue, for the most part, we happen to live in a variant that has succeeded better, so far.
The GR1B is a Tornado variant that has been optimised for maritime strike missions with the Sea Eagle anti-shipping missile.
In some instances, however, selection may act on a new single variant that has a major effect on a phenotype of interest4.
We have developed a new cocaine-binding aptamer variant that has a significantly higher melt temperature when bound to a ligand than the currently used sequence.
Hemoglobin Le Lamentin (α20(B1)His → Gln) is a ubiquitous variant that has been previously described in a small number of isolated patients.
The Glenlivet 12-year-old, for example, is available in a variant that has been finished in a barrel made from Limousin oak, Quercus robur, from France.
We next tested the properties of an Adamts3 variant that has a heterozygous arginine 565 → glutamine (R565Q) missense substitution in the thrombospondin type 1 (TSP-1) motif of ADAMTS3 (Fig. 6a).
Trappin-2 A62D/M63L, a trappin-2 variant that has no antiprotease activity, has similar properties, suggesting that the anti-inflammatory action of trappin-2 is independent of its antiprotease activity.
Meanwhile, the Model 3, which has a base price of $45,000 for a new rear-wheel mid-range variant that has a 260-mile range, sits alone.
Meanwhile, the Model 3, which has a base price of $45,000 for a new rear-wheel mid-range variant that has a 260-mile range, sits alone.
