Sentence examples for variant that encodes from inspiring English sources

Without disrupting of the inserted gene's function, TEs can expand the proteome diversity by adding the splice variant that encodes a different, yet functional protein.

According to the ascribed role of AS as a mechanism for expanding proteome diversity, a gene can become polymorph in its expression through an additional splice variant that encodes a different, yet functional protein.

The p73α isoform is the only C-terminal variant that encodes for a fully functional Sterile Alfa Motif (SAM) [ 97- 99], that has been identified as a repressor of transcription and apoptosis [ 100- 102].

Goto and colleagues subsequently isolated a variant that encodes a third UIM at its C-terminus instead of this hydrophobic tail [11].

Direct typing of the genetic variants that encode the HLA alleles is usually very difficult since most of these variants are surrounded by too many other variants that interfere with primer annealing.

The NR3C1 gene is known to contain at least 11 untranslated 5' exon 1 splice variants that encode a common protein via a splice acceptor site on the exon 2. In this way, tissue-specific expression of NR3C1 is regulated by alternative splicing [30].

Milk protein genes exist in different genetic variants that encode proteins that are slightly different chemically.

All available data suggest that slow NAT1 phenotype results from NAT1 allelic variants that encode reduced expression of NAT1 and/or less-stable NAT1 protein [ 15].

When FL-cDNA information is not available, splice variants that encode the longest ORFs were selected as representatives for subsequent sequence alignments.

To amplify the mRNA transcript variants that encode the full-length KLK6 protein (GenBank accession no.,,, and ), we designed primers (for sequences see Table 1; Figure 1B) that anneal to a common region for all four variants (nucleotides 257 709; numbers refer to GenBank accession no. ).

We analyzed medulloblastoma samples from thirty-four pediatric patients and the established medulloblastoma cell lines, Daoy and D283MED, for expression of TP73 RNA including the full-length transcript and the 5'-terminal variants that encode the ΔNp73 isoform, as well as TP53 RNA using quantitative real time-RTPCR.