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Exact(5)
For another variant that did not replicate at genome-wide significance in this study, rs1571801, the previously reported association with PrCa achieved statistical significance only in relation to aggressive disease (11).
R199P was identified in a Leigh syndrome patient as compound heterozygous with R88G (a variant that did not assemble Y. lipolytica complex I), and no biochemical data were reported (see Supplementary Material, Table S2) (24).
Interestingly, R388S, also located in the C-terminal α-domain, was the only variant that did not require co-overexpression of GroESL for tetramer formation and its proteolytic and thermal stabilities were only moderately affected.
As shown in Table 5, the SSRs with 3, 6, 9 and 12-bp variants comprised significantly larger fractions than the other types, suggesting that the SSR type and repeat variant that did not cause frameshift mutations were preferentially selected during evolution.
Further, the robust level of expression of variant gsv4,5, the only variant that did not contain an amino acid substitution at position 47, is consistent with the hypothesis that N-glycosylation at this position may be critical to ICAM-2 protein structure and stability.
Similar(55)
We evaluate our approach by grasping objects that were not seen at training time, and compare to an open-loop variant that does not perform continuous feedback control.
A mutant APC variant that does not associate with PSD-95 did not enhance microtubule bundling, despite coexpression with PSD-95.
The shady west-facing backyard is fenced in cedar and granted privacy and perma-green vistas by a bamboo variant that does not shed its leaves in winter.
When we expressed MFG-E8-C2 AAA)::GFP, MFG-E8-C2 AAAt does not bind PS due to the replacement of these three residues to alanines21, no increase in fluorescence localization was observed followinGFPxon injury (Fig. 4a, b and Supplementary Fig. 8).
Alas, its been absolutely, positively confirmed that this one doesn't have a front-facing camera, making the Epic 4G the only US variant that does.
An explanation for this sudden breakdown can be found when considering (55) in conjunction with (62), which describes a GFDAF variant that does not exhibit this property.
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