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If the new variant strains generated by drift are significantly different from predecessor strains, cross-protection conferred by vaccination or natural infection may diminish, thereby enabling antigenically drifted viruses to effectively escape from herd immunity [ 21].
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Mutant sequences from synthetic TEM gene variants and from TEM gene variants in bacterial strains generated large increases in fluorescent signal relative to that from the reference sequence for TEM-1.
The model presented above has some explanatory power beyond that of conventional theory in that it suggests that for Influenza A new pandemic variants generated by antigenic shift will be more pathogenic (assuming pathogenicity correlates with infectious duration) than the subsequent seasonal strains generated by the process of evolutionary antigenic drift.
Variants at each HVR have been frequently exchanged across bacterial strains, generating highly chimeric proteins [ 31].
Copy-number variant regions were generated by extending variant windows and merging neighboring variant regions.
All the genome fragments depicted in Figure 4 were found to have 100% identical homologous sequences in strain CA. This is not surprising, as A. vinelandii DJ is a variant of strain CA generated in 1984 [ 18].
New strain variants are generated through the cycle.
Thus, the XDH variants EB232V, RB310M, and the double variant EB232V/RB310M were generated.
The [ PSI+]Weak variant (SY2126) was generated by mating SY2125 to a WT [ PSI+]Weak strain (SLL2600) and sporulation.
S.R. outcrossed the strains and generated the reporter strains.
In order to test the simultaneous effect of G5-SSR426 C6-SSR431R431 on the emergence frequency of mucoid variants, a new strain was generated (MPA-T3) which carried both SSRs (G5C6SSR426) (mucA-T3 allele) (Figure 1).
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