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The introduction of the polar L172Q variant (shown in magenta; Figure 4) into the non-polar environment at the core of the protein is likely to disrupt this environment as it seeks to accommodate the new polar residue.
Modification of the effect of HRT use on breast cancer risk by the KRAS variant shown in our study is highly reasonable.
In these mice human FUS protein identical to the NT variant shown in Figure 1C, but without GFP tag, forms multiple cytoplasmic and nuclear inclusions in selected neuronal populations.
Similar(57)
Allele1 allele 4 are the variants shown in Figure 1.
These structurally similar variants are more likely to encode products with similar biological function, as in the case of p63 variants shown in Fig.1.
Of the other splice variants shown in Figure 2, all were confirmed by strand-specific RT-PCR to be "forward" (Orly) transcripts (data not shown).
The Drosophila PAS is remarkably similar (details in Table 2), and the differences reflect the slight variations in proportion of different variants shown in table 1.
This is evident in the wide variety of property combinations for the studied library variants shown in Figures 1(B), 2(A) and 2(B).
The functional characterization of other conserved splice variants shown in our study may also prove important in vertebrate cAMP signaling pathways.
(C ) Co-localization index for mRNA recruitment into foci of Ire1 variants shown in B (mean and s.e.m., n = 5 10).
(G ) Micrographs (size bar, 10 μm) and corresponding kymographs of hyphae expressing Upa1-Gfp variants shown in Figure 4 (Videos 6 9 ).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com