Sentence examples for variant presented a from inspiring English sources

However, the putative 3D structure of the variant presented a number of problematic issues.

In an in vivo study by Crettol et al. [14] the carriers of the CYP3A4*1B variant presented a 1.4-fold increase for (S -methadone and 1.1-fold increaS -methadoneethandne; also, the CYP3A4*1B variant carriers have more probability to be in the low-dose group, suggesting that they have higher methadone plasma concentrations and require lower methadone doses.

The effect of at least one NQO1 rs1800566 (C609T) variant presented an increased risk association with ALL with MLL-r, although not statistically significant (p = 0.09).

In fact, the incommensurate modulation is related to an orthorhombic basic structure, while the commensurate variant presents a monoclinic symmetry.

In five additional cases, a novel variant, presenting a G351 to A mutation, in the reactive centre loop of the protein, was identified and termed SCCA-PD (GenBank accession number: AY190327).

Four of the seven HID variants presented a dominant neuroendocrine differentiation and five a dominant mucinous phenotype.

A total of 80 variants presented a possibly damaging or deleterious consequence as predicted by at least one of them (Fig.  2b).

In comparison to patients bearing VEGF -1498 C/C genotype those with-1498 C/T and T/T variants presented a higher risk of progression and death with an additive effect of each T allele (Table 2).

The differences are mainly related to the number of exons as follows: neuronal variant presents an extended exon 6, the spleen variant is characterized by the absence of proline-rich region, and the breast variant has a supplementary exon 11a [ 1, 2, 4, 10].

Similarly, variants presenting a DS <14 in the control file were discarded (see above for explanation).

While knowledge regarding rare variants is becoming increasingly detailed, statistical analyses of rare variants present a number of challenges.