These networks comprise all possible variants of the core Lys-Lyt mutual repression motif and include over 95% of successful networks.
The variants are of three basic categories: variants of the core motif; single nucleotide polymorphisms (SNPs); and genomic occurrences (Table 1).
In order to discover the evolutionary history of basal chromatin modifying mechanisms, we decided to undertake combined phylogenetic and molecular biological analyses focusing on variants of the core histone H3 and its PTM signature.
H1.0, H1.2, H1.3, H1.4, H1.5, H1.5 and H1X are the variants of H1; H2A.X, H2A.Z, H2A-BDB and Macro H2A are replacement variants for H2A; and H3.1, H3.2, H3.3 and CENP-A are variants of the core histone H3 (Fig. 1C, for review see ref. 27).
In addition, by looking at model variants of the core iPS regulation, it was shown that an increased chromatin modification rate could improve reprogramming efficiency while faster changes in DNA methylation could provide an enhanced rate though at the price of trading-off efficiency.
A new variant of the shrinking core model (SCM) best fitted the kinetic data in which both the interfacial transfer and diffusion across the product layer affect the reaction rate.
Repeated leaching tests on tailing samples of various chemical and physical properties have been performed and the electrical conductivities measured fitted well into a new variant of the shrink core model, which is suggested as a simple test method to predict the potential salinity generated by tailings.
To effectively observe the alterations of polymerase function in six selected pol ι variants of the polymerase core domains, we utilized the core protein (amino acids 1 445) of pol ι, which contains all the polymerase core domains critical to polymerase activity.
Obese subjects carrying the CLOCK 3111TC/CC polymorphism, a variant of one of the core clock genes associated with being an "owl" or an evening person, sleep 20 minutes less.
