Similarly, the U1013 antibody recognizes a major band Xinα of size 217 kDa (* in Fig. 4), its splicing variant of size 282∼295 kDa (** in Fig. 4) and some degraded fragments (160∼198 kDa) from turkey, chicken, frog and zebrafish heart extracts.
However, for each PSHET the line with the heterozygous INDEL call had a variant of size 13 bp on average.
Throughout the manuscript we will refer variants of size ≤1 kb as short CNVs (sCNVs).
Whereas, within variants of size >1 kb, variants involving copy number gains are overall more effective than deletions (p = 8.5e-05 8.5e-05e 4A).
Using data generated for a subset of individuals by a 42 million marker platform, we validated the majority of the variants with the highest validation rate (66.7%) was for variants of size larger than 1 kb.
This is unsurprising, as all extended COI variants share identical regions with other variants of size ≈ 250 bp.
Transcript variants of this gene, with sizes of 4,700 bp and 4,200 bp, have been previously reported in human and transcript variants of size 4,200 bp and 2,900 bp have been reported in mouse [ 29, 30].
In most recreational fisheries, some variants of size-based harvest regulations are used to maintain recruitment, manipulate the size structure of the fish stocks, or distribute the harvest more equitably among anglers (Arlinghaus et al. 2002).
First, from an evolutionary perspective, a 'gene' represents a haplotype variant of indeterminate size, with larger haplotypes more likely to exert greater phenotypic effects (that may be selected for or against) but less likely to avoid being broken apart by recombination.
To test whether these sequence differences might impact on promoter function we determined the effect of two sequence variant alleles, both of size "1", using the luciferase reporter system.
This indicates that individual common genetic variants of this size or greater do not contribute to personality trait variation, which has important implications regarding the genetic architecture of personality and the evolutionary mechanisms by which heritable variation is maintained.
