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While the "less grateful" version of the COMT gene isn't all bad there is evidence it has advantages for memory and attention the results reported by Liu and colleagues suggest that this gene variant may also predispose people to be not only less sensitive to positive life events but also super-sensitive to negative life events.
The Phase 2 trial provided further evidence that the MTHFR variant influences treatment response and that the MTRR variant may also be acting independently to influence vitamin treatment response in migraineurs.
The differential mRNA expression shown for SNTG1 suggests that its intronic variant may also serve as an intronic enhancer.
Our strategy focuses on deleterious rare variants: other types of genetic variant may also influence SUDEP risk.
Hence, the U2 splice variant may also play vital roles in RNA polymerase II transcription and/or co-transcriptional mRNA processing [ 12].
This third variant may also be located in a welfare state reform context, but in a different idea of reform emphasizing community development.
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Natural polymorphisms and alternative splice variants may also contribute to their pharmacological diversity.
As well as overall risk, certain gene variants may also correlate with particular presentations of IBD, Ananthakrishnan says.
Despite the evidence showing the contribution of these loci to AD pathogenesis, their genetic architecture has not been extensively investigated, leaving the possibility that low frequency and rare coding variants may also occur and contribute to the risk of disease.
Moreover, it appears likely that, in addition to BRCA1 associated protein 1, other yet unknown genetic variants may also influence the individual risk for development of MM, especially after exposure to asbestos and related mineral fibers.
One or more structural variants may also be contributing [57].
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