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In contrast, this substitution was only seen once (a unique variant) in the reported avian H7N9 viruses, but was predominantly observed in the human viruses as the index, possibly indicating a role in host tropism.
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We also replicated additional variants in LD with the reported SNPs in ZMAT4 and adjacent to IRS1.
Possible interactions of the TNFα SNPs with variants in the previously reported IL1β and IL6 genes in influencing hand OA were also explored.
One variant mentioned in the report is antimatter-catalyzed fusion, which drives a spacecraft with a series of thermonuclear explosions.
The coding variant in LIPG (rs61755018) reported by Voight et al. was not significantly associated with HDL concentrations in our cohort [ 4].
However, when we comprehensively evaluated all HapMap variants in linkage disequilibrium (r2≥0.3) with the reported variants, the transferability rate increased to 54.1%.
The reported variant in Landseer dogs introduces an early stop codon into the open reading frame.
After synonymous variants were filtered out, there were 11,428 variants (including 239 variants not reported in the dbSNP135) to be examined for candidate mutations.
At some point, it becomes possible to provide more information about the significance of the variant in diagnostic reports, both to the original family and to subsequent families who may have the same variant.
The high incidence of this variant in the C9ORF72 expansion carriers was reported in the initial publications [ 2, 3].
It should be noted if the variant has been reported previously in the literature or in disease or control databases.
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