Sentence examples for variant in control from inspiring English sources

To compare between different experiments, these values were calculated as % of the respective value for the exon included splice variant in control cells treated with low K.

Interestingly, this list contains 8 genes expressed in both liver and kidney (Cyp2d26, Tf, C3, F2, ApoE, Spp2, Rbp4, Rn.107069) that were highly variant in control kidney, but among the least variant in control liver samples.

Their minor allele frequencies in cases and controls were of 0.087 0.091 similar to the population frequency reported previously for this variant in controls.

The frequency of the variant in controls ranges from about 1.3% in the Netherlands and Finland to 0.52% in UK and to about 0.2% in Germany (CHEK2 Breast Cancer Case-Control Consortium, 2004).

Evaluation of evidence used to identify mtDNA mutations in other mtDNA genes indicates that the absence of the variant in controls is important evidence of pathogenicity.

The genotype frequencies of the HFE variant in controls and in patients with and without IOL were significantly different (p=0.0013 and 0.0002, respectively), higher in patients with and without IOL.

In our present study, 13 variants in control group and 11 in case group were detected.

For the detection of somatic variants, a bimodal strategy was applied with tumor variants called under stringent criteria, whereas variants in control tissue were called using less stringent criteria: A minimum threshold for reads was set with variants of 15% of all reads at a given position in tumor.

The "noise" introduced by these splicing variants in control samples ensures that we are testing the variant containing samples against samples with many, distinct, splicing mutations.

However, the probability to observe 3 or more variants among 148 individuals by chance based on the frequency of SLC7A3 variants in control populations is very low (p = 0.05), supporting an excess of SLC7A3 variants in patients with ASD.

We used a large number of positive control mutations to validate this capture method, and in the process uncovered a variety of genomic variants including small and large deletions, and single nucleotide variants in control patients.