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Both a natural HpSVd-hop and -grapevine variant, in addition to an in vitro transcript of HpSVd-grapevine, were introduced into hops and cultivated over 15 years.
Five patients (5/52=9.6%) showed a novel variant in addition to a pathogenic allele in a recessive gene.
Interestingly, all of these haplotypes contain the A-allele of CSN2_67 (the A1/B variant), in addition to the G-allele of CSN2-BMC_9215 (Additional file 2).
A new variant (in addition to a preexisting variant) was detected in posttreatment samples in 6/15 (40%) patients (Table 1; Supporting Fig. 2A-C).
Model 8 was a bit different in that it contained a moderate main effect for one genetic variant in addition to a stronger three-way interaction.
Indeed, CGC 7 speculated on a possible compound genetic effect of the GLA variant in addition to the causal MYBPC3 mutation, but could not report this with certainty.
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Furthermore a PCR amplifying the pilin locus was performed on Z5463BC without starting from an isolated colony and cloned in E. coli, eight of these clones were sequenced, they identified an additional two pilin variants in addition to the above four (Fig. 7).
Steck, A. K. et al. Improving prediction of type 1 diabetes by testing non-HLA genetic variants in addition to HLA markers.
These images (there are at least four variants, in addition to video footage), of an unknown solitary protester standing in the way of advancing tanks, encapsulate the plight but also the greatness of an individual taking extreme personal risk.
Our results have the potential to increase the power and interpretability of association studies by targeting functional intergenic variants in addition to protein coding sequences.
We created a series of double and triple variants in addition to the single variants H236K, H236I and H236R (see Table 3).
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