Sentence examples for variant cells have from inspiring English sources

These findings further confirmed that the intracellular domain of the EGFR is indeed altered causing diminished receptor internalisation and/or degradation and as a result DiFi62 drug-resistant variant cells have an increased extracellular expression of EGFR.

While Fra-1 mRNA levels were not significantly regulated in the MDA-MB-231 cell variants, immunoblots, EMSAs and chromatin immunoprecipitations showed that the metastatic variant Scp-2 cells have higher Fra-1 protein expression and higher DNA binding in vitro and in vivo to the MMP-1 AP-1 site.

4, 25 Variant SCLC cells had a faster growth rate and higher metastatic potential in an experimental metastatic model than classic SCLC cells.

The original method uses autoradiography to detect 3H-thymidine incorporation in variant cells that have undergone DNA synthesis; the bromodeoxyuridine modification employs this thymidine analog and fluorescence plus Giemsa staining.

Antibodies and antibody variants produced in myeloma cells have been extremely helpful in elucidating the amino acid residues and structural motifs that contribute to antibody function.

New metastatic variants of Rama 37 cells have been generated.

Single cell-derived MCF-7 clone and its tamoxifen and fulvestrant resistant variants of MCF-7 cells have been described previously and were gift from Dr. Ken Nephew [ 44].

However, other mechanisms of bacterial latency such as phenotypic variants leading to persister cells have also been described [ 1], and are increasingly encountered in the clinic.

It is conceivable that differences in p53 status have an impact on differences in the sensitivity of cells to MN-inducing agents, although evidence from experiments with p53 deficient variants of human TK6 cells have revealed little influence of p53 status on MN formation (Hashimoto et al. 2011; Honma and Hayashi 2011).

However, if a beneficial variant emerges, the prion-carrying cells have the potential to take over the colony ensuring survival under adverse conditions.

However, the differences in the localization, expression, and function for the two splice variants of KIF23 in tumor cells have remained largely unknown so far.