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To demonstrate that long-chain fatty acids are efficiently excluded from the A134F variant both in vitro and in vivo, whole-cell biotransformations were performed.
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In conclusion, antiviral treatment may favor emergence of new 5′UTR variants both in blood and in PBMC compartments.
The function of ITSs can be inferred from the association of heritable diseases with ITS polymorphic variants, both in copy number and sequence.
Although T-20 effectively suppresses the replication of multi-drug resistant HIV variants both in vitro and in vivo, prolonged therapy with T-20 induces emergence of T-20 resistant variants.
We found several heterozygous variants both in patients and controls.,Two of the variants are novel and present only in PD cases (p.R334H and p.A46T).
Here we present evidence that the PKA inhibitor H-89 attenuates the bioluminescence signal produced by RLuc variants both in cells and in vitro.
Subjects S2 and S4 harbored X4 variants both in PBMCs and the thymus, and were selected for an in depth study of in vivo evolution of R5 and X4 quasispecies.
This finding emphasises the need to investigate the properties of newly discovered hGALE variants both in vitro and in model in vivo systems.
TRiCs inhibition of mhtt aggregation has been biochemically characterized for several variants both in vitro and in vivo (Kitamura et al., 2006; Tam et al., 2006).
We found that the APOL1 missense variants (rs73885319 and rs60910145) are more strongly associated with ESKD risk than the leading MYH9 risk variants, both in terms of OR and p values (Table 1).
Utilizing heteroduplex analyses, we have identified a number of sequence variants in COL7A1 both in unaffected individuals and in patients with M-RDEB.
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CEO of Professional Science Editing for Scientists @ prosciediting.com