Further, a critical Arg in the E. coli variant at the substrate-binding site is replaced by Tyr in LDGLOI.
This effect is less pronounced in the first algorithmic variant at the expense of a higher computational cost.
The activity at high substrate concentrations is increased with the W397A variant at the expense of a lower substrate affinity (Fig. 4a, b).
We identify eight loci passing genome-wide significance, secondary independent effects at three loci and a distinct PsA-specific variant at the IL23R locus.
Tuncman, G. et al. A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease.
They identify a variant at the TERT-CLPTM1L locus on 5p15 as associated with ER-negative and triple-negative breast cancer.
To study a new sequence variant at the beginning of the CAG repeat in the exon 1 of the androgen receptor gene.
The most popular Wi-Fi variant at the moment, 802.11b, is also much faster than Bluetooth, operating at up to 11 million bits per second -- or about eight times the speed of D.S.L. and cable modems.
Our study revealed that binding of calnexin C-tail on the III-IV linker lacking the exon 25 is significantly decreased, which correlated with an increased expression of the Cav3.2 (−25) channel variant at the cell surface.
Finally, we identified 134 MS patients homozygous for the risk or protective variant at the MS Clinics in Yale, USA and Turku, Finland, to determine their lesion load on MRI.
In a separate study, we identified 127 MS patients homozygous for the risk or protective variant at the MS Clinics in Yale and Turku to determine their total brain volume on MRI.
