Sentence examples for variant and of from inspiring English sources

However, DAE-based approaches can point out the presence of a regulatory causative variant only if the subjects are heterozygous for the causative variant (and of course for the coding SNP serving as marker).

Analysis of the distribution of HGMD-DM variants showed that 35%% of individuals (3871 out of 11,068) have at least one DM variant and of those 847 have two or more (Fig.  3).

As our focus is on a dichotomous outcome, i.e. the presence or absence of a variant at a particular position, we use here the probabilities of identifying the variant at a site that carries a variant and of identifying no variant at a site where only the reference sequence is present.

All variations were identified both in mixed and unmixed samples, with the exception of the homozygous c.1014G > C polymorphic variant and of a base substitution in exon 7 (c.544C > G; p.Arg182Gly); the latter was present in a single sample, in homozygosity, and could be detected only after mixing with reference DNA. 1 In bold novel variants identified in this study by HRMA.

Power simulations, based on the entire sample of patients diagnosed with chronic tinnitus and on published control data, indicated that we should expect a statistical power of >80% to detect a susceptibility factor with an allelic relative risk of >1.56 for the F66F variant, and of >3.27 for the R83H amino acid exchange.

Cellular equilibrium binding studies with the monomeric scFv l αhCD70 protein and the trimeric scFv l αhCD70-TNC-GpL molecule on Mino and OVCAR3 cells yield KD values of 2300 and 1300 pM for the monomeric scFv variant and of 160 and 240 pM for the trimeric variant.

Freecell is a notoriously difficult variant, and some of the hands you're dealt aren't actually solvable.

Novel Splicing variants and loss-of-function variants such as nonsense mutations, frameshift deletions or insertions.

Itsara, A. et al. Population analysis of large copy number variants and hotspots of human genetic disease.

Some variants and examples of empire have proved powerful and durable.

Important process variants and designs of biological filters are explained.