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Bioequivalence was assessed for the primary and secondary endpoints using a mixed effects analysis of variance, with terms including subject within sequence as a random effect, and study drug and period as fixed effects.
The summary scores of SPID, TOTPAR, and SPRID from 0 to 2, 0 to 3, 0 to 6, and 0 to 8 hours, as well as PR, PID, and PRID scores at each postdosing time point, were analyzed by analysis of variance with terms for treatment, sex, and baseline pain severity in the model.
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The intrarater reliability was measured with the use of the intraclass correlation coefficient (ICC = σ 2patients/(σ 2patients + σ 2error)) from a 2-way analysis of variance model with terms for patient and measurement trial.
Comparison of treatments at baseline was accomplished using an analysis of variance (ANOVA) with terms for treatment and site.
Furthermore, to test for interaction effects of group allocation and measurement time, we conducted two-way analyses of variance with interaction terms (cf., Table 4).
A multivariable analysis of variance with appropriate terms for interaction was used for testing the association of adherence to MD scores, dietary patterns or dietary variables (considered as the dependent variables) with categories of income or SES components.
Outlining his recipe for tackling the crisis, Hollande called on Germany to help rebalance the eurozone economy by cutting taxes and raising wages to spur domestic demand and proposed policies sharply at variance with Berlin in terms of timing and sequencing.
The comparison of the change magnitude between TP and TN group was performed using an analysis of variance with the interaction term between the group and time.
For statistical analysis, all experiments were analyzed for deviation from additivity with an n-factor analysis of variance with an interaction term, n being the number of components tested in combination.
Short-range decomposition of Fe-Ni solid solution and difference in Fe-H and Ni-H bonds are responsibondsor the splitting of γ reflections in X-rarediffresponsibleterns, which is at variance with common interpretation in terms ofor hydrogen-caused γ* phase.
Following West et al. [ 26] and Zuur et al. [ 24], the most appropriate variance covariate matrix was determined using AIC scores in conjunction with plots of fitted values versus residuals with different variance covariate terms relating to the independent variables, using restricted maximum likelihood (REML, [ 26]).
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