Exact(2)
To estimate the sampling variance (robustness) of population structure inference, five independent runs were carried out for each k.
Therefore, we were surprised to find a negative correlation among disruption strains in their degree of variation in response (i.e. variance robustness) to environmental and mutational stresses, with only one outlying strain (the fis-deleted one) disrupting a statistically significant correlation.
Similar(58)
It is instructive to compare this low variance in robustness to that predicted by a simple probabilistic argument, where each reaction contributes independently to mutational robustness.
Unfortunately, the EPE statistics in (27), like the sample mean and sample variance, lacks robustness towards outliers [21 23].
In order to account for the effect of uncertainty in the model parameters, mean-variance robust optimization is performed, allowing a trade-off between performance and robustness.
This interesting outcome is entirely consistent with the greater constancy of phenotype expected for robust genotypes relative to brittle ones, despite the greater genetic variance predicted under robustness.
Analysis of variance (ANOVA) of robustness factors.
If s is the number of super-essential reactions, the expected variance of mutational robustness then becomes p 1-p n-s)/n2 where p 1-p n-ss).
However, this correlation alone cannot explain the co-variance of genetic robustness with position in the protein interaction network.
Additional work tackling simultaneous modeling of heterogeneous genetic variances jointly with heterogeneous error variances and potential outlier robustness extensions is warranted.
This robustness towards variance in the partner's behavior also applies to memory errors, which makes the assignment of types a good strategy with high memory load.
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