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Previous studies have shown that the variance of intensities tends to grow linearly as a function of the intensity levels (heteroscedasticity) [34].
Considering that the variance of intensities in real or realistically simulated data would broaden the LLR distribution and thus result in a smaller p-value, typically a small p-value of 10−3 to 10−6 is used as the threshold in our analysis and is still sufficient to reject incorrect models and the un-converged fit.
Given the highly skewed nature of the raw spot intensities, the dependence of the mean and the variance of intensities, and the fact that even the non-parametric Wilcoxon test assumes symmetry in the outcome variable [ 17], log transformation of the data is still advisable.
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Separable and multiple eyelashes are detected using 1D Gabor filters and the variance of intensity, respectively.
where IM(S i ) is the Importance Measure as (7) and is the variance of intensity values in S i (sub image i).
This method outperformes simple thresholding algorithms, as they tend to fail due to the high variance of intensity values on OCT images.
> -wrap-foot> The intensities were scaled to the mean intensity in the pelvis region to facilitate the comparison of the different normalization approaches The variances of intensities within the tissue after normalization using TIC, RMS, or median is significantly reduced compared with the non-normalized sample.
The vasculature was identified as regions of motion by creating LOGIV and DLOGIV tomograms: multiple B-scans were collected of individual slices through the retina and the variance of logarithmic intensities and differences of logarithmic intensities were calculated.
The ranges and variance values of intensities are closer to that of SSP 1733 (spot with no missing intensities) in the case of multiple value imputation.
The variance of log2 intensities of the normalised arrays intensity fall within acceptable limits for comparison.
A closer look at any gene interval reveals that the variance of probe intensities increases proportionally to the CN, i.e. the variance of the intensities can vary in-between CNs and samples (Fig. 2).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com