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The variance in the proportion of mutant virus (Fig. 4, pale regions) increases with each additional mutation required because of the increased number of combinatorial options and the greater selective advantage of mutant viruses as compared with wild-type viruses in the hill-climb scenario.
Decomposition of variance in the proportion of TB cases (per 100,000) among migrants into its components revealed seasonal, non-seasonal and random components as 55%, 32%and13%3% respectively.
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The overall regression model (not including age, gender and region) showed a statistically significant increasing tendency and explained 59.4% of the variance in the proportions observed (figure 2).
Proportion explained variance was calculated according to Snijders and Bosker [ 13] by comparing the proportion unexplained variance in the full model with the proportion unexplained variance in a model with only random effects.
We found in simulations that ignoring epistasis leads to a slight overestimation of the additive variance in proportion to the amount of epistatic variance (Table S3 and Table S4), as well as underestimation of the standard error.
The intraclass correlation coefficient estimates how much of the total variance of the test retest dataset originates from the measurement error (within-subject variance) in proportion to the intersubject variance (range −1 to 1).
Singer and Willett define pseudo R-squares for each variance component as the proportion reduction in the component in comparing the larger model to the smaller model [ 18].
Distances between tissues were calculated, based on variance in mixing proportions, as the sum of the square of the difference, for every Tm category, of the mixing proportion between a tissue and the average of tissues.
The guild proportionality null model [21] tests the probability that the variance in guild proportions across sites is lower than expected by chance.
For tossup states, the variance in vote proportions is fairly low since the two major-party candidates will have close to the same proportion.
The inclusion of TPB determinants explained the largest proportion of variance in the regression models, however the sizes of theses proportions are still limited.
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