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This is variance in correlation between neighbors of a protein and is defined as: <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0006017.e005.PNG" class= inline-graphic"/> PCC variance (vPCC), reflects the variation in the co-regulation of proteins in the neighborhood.
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Second, the scatterplot shows heteroscedasticity higher variance in correlations for smaller than for larger sample sizes, as expected from the Central Limit Theorem if there is no publication bias towards either larger or smaller effect sizes.
Other studies have found higher correlations between O3 and PM10, and O3 and temperature [ 16], and substantial variance in the correlation between O3, PM10 and NO2 in different cities in Italy [20].
In practice, however, the groups were very small and resulted in high variance in average correlation coefficient, such that of 51 TFs with >2 genes in their group, 21 had negative correlation.
Future research would benefit from the identification of additional socio-ecological factors that mediate long-term among-year variance in the correlation between pairs of behaviors, and also from deeper studies on within- and between-individual correlations that are manifested on longer time scales (e.g., among years).
The goal is to achieve parsimony by using the smallest number of explanatory concepts to explain the maximum amount of common variance in a correlation matrix [44].
Together, they explained 47%% of the variance in the correlation matrix.
Extraction of four factors provided the clearest solution, accounting for 44% of the variance in the correlation matrix.
The factor analysis resulted in six factors with eigenvalues greater than 1.0 and accounted for 69% of the variance in the correlation matrix.
Analysis of the participants' Q-sorts resulted in four discrete perspectives (a four factor solution), accounting for 71% of the variance in the correlation matrix (Table 2).
The two-factor solution contained meaningful (0.35 or greater) loadings for the seven PEACE scales and accounted for just over 60% of the variance in the correlation matrix.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com