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Conceptually, this variance forms a "strip" where all samples that lay within its boundaries are influenced by internal noise only.
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This illogical result is due to the large variance formed by the binomial distribution explained in Appendix "Hypergeometric distribution".
For a comparison, the advantages and disadvantages of other measures such as kurtosis, mean, variance, form factor and crest factor, both of residual signal and mean amplitude of continuous wavelet transform waveform, are also discussed.
On the technological side, at variance form the traditional telemonitoring of COPD patients, monodimensional in nature or, if multidimensional, based on cumbersome technological tools and procedures [ 20], our telemonitoring system was very easy to use: the patient had to do little more than wearing the device.
In addition, we show how random effects analysis of variance, which forms the basis for ICC, can be used to derive additional test-retest metrics, which are generally not reported in the PET brain imaging test-retest literature, such as within-subject coefficient of variation and repeatability coefficient.
The first component, which accounted for 37.06% of the total variance, was formed by P, A, He, and AL (Additional file 7: Table S7).
The second component, representing 29.49% of the total variance, was formed by N, LN, and RA, while the third component represented 19.06% of the total variance, which composed of LA, T, and HU.
The variance components formed the covariance structure and the containment method was used to compute the degrees of freedom.
For multivariate analyses, PCA (unsupervised) and PCA-linear discriminant analysis (PCA-LDA; supervised) were performed to facilitate the identification of segregation of the spectra, based on variance, by forming linear combinations of the wave numbers and ranking them in order of variance (Matlab 2012a; The Mathworks) (27, 28).
The relative proportion of C>T/G>A changes was highly significant compared to other nucleotide changes (p < 0.0001, Kruskal Wallis one-way analysis of variance) and formed 32% of all nucleotide changes overall, a proportion that was double what was expected due to chance.
We focus on the quadratic mean-variance functional form with local estimates from here forward for four reasons.
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