Epigenetic mechanisms create variably stable changes in gene expression through the establishment of heritable states of chromatin architecture.
They also concur with the findings of several earlier studies that found environmental enrichment consistently prevented cognitive decline in AD model mice, but changed the amount of senile plaques variably, according to the experimental conditions (the senile plaques increased [31], decreased [32], or remained the same [33] despite the consistent cognitive improvement).
Clearly UHRR is not representative of breast tumour RNA and therefore carries no guarantee of expressing RNAs that may be variably expressed in the specific subset of genes changed in breast tumour tissue.
Deeper within the pyrenoid, pyrenoid tubules began to twist, sometimes abruptly changed direction by >90°, and eventually lost their cylindrical structure as the tubules converged at the pyrenoid center, forming elaborate interconnected networks of variably shaped smaller membranes.
However, in rodent aging, researchers have variably reported no change in sleep [61], reduced or fragmented sleep [46], or changes in REM sleep [45], [62], [63].
Student's beliefs may also change over time, which may variably impact their ability to participate in learning activities.
These changes occur variably in concert with the development of spontaneous recurrent seizures in humans and in animal models of inducible TLE.
We included for analysis the 4,824 cDNAs (corresponding to 3,413 unique genes) that were well-measured (intensity/background >2 in either the test or reference channel) in at least 50% of samples, and variably expressed (>4-fold change from the median) in at least 3 samples.
Those changes were variably associated with dense cytoskeletal-like cytoplasmic strands and junctional abnormalities (Fig. 3C).
31 It is therefore biologically plausible that genetic variations in 5HT3B may variably modulate morphine-related changes in breathlessness perception while fentanyl has no effect.
