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Prior systematic review of the literature along with expert opinion guided the selection of variables to be collected.
For a new project, data variables to be collected for each data record (sample) are firstly defined.
This allowed the generation of hypotheses and informed the choice of variables to be collected.
Other variables to be collected during this period are: the appearance of important diseases, the taking of osteopenic drugs and the use of walking aids.
Therefore, we are limited by the original choice of variables to be collected, and the measures of early development or of social environment may only be indicators or markers of risk rather than risk factors themselves.
Our analysis at this stage differs from that of Sperduto et al.[ 2] in so far that we believe that the RPA score is more readily reproducible in practice thanks to a limited number of variables to be collected and fewer prognostic classes.
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However, it can only be done on a single species basis and so the same two variables have to be collected for all species in the fishery.
The requirement of informed consent was waived because the IMC was included in the usual care and no extra variables had to be collected.
The second characteristic for rigorous prediction is that all predictor variables need to be collected for the previous time period (e.g. week) and be used for prediction of outbreaks during a later time period.
Assuming they would have selected the Mazmanian and Sabatier model [ 42], this would have led to the careful operationalization of variables and data to be collected – rather than drawing on a fairly randomly selected collection of informants and media expressions.
Data on potentially confounding variables will be collected to help inform interpretation of results.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com