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Differences in the distribution of continuous variables between groups were analysed using the two-tailed independent t-test.
Nonparametric tests and χ(2) tests were used as appropriate to compare variables between groups.
The Wilcoxon rank-sum test was used to compare interval and ordinal variables between groups.
The unpaired t test was used to compare demographic variables between groups.
Fisher's exact test was used to compare nominal variables between groups.
Chi-square tests were used to compare the distributions of categorical variables between groups.
No differences in any of these variables between groups were present at baseline.
Univariate comparisons of continuous variables between groups were carried out using Mann–Whitney U test.
The chi-square test was used to compare categorical variables between groups.
Chi-square tests were used to determine statistical significance for categorical variables between groups.
Differences in continuous variables between groups were calculated using a two-tailed unpaired t-test.
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