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The density of variables and contingencies mean that one thing can really change everything else".
The classic example of this type of problem is figuring out the most efficient way a traveling salesman can visit 10 customers, but real-world problems now include hundreds of such variables and contingencies.
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Thus, we prepared the data to perform three statistical analysis: descriptive analysis of all variables, Chi-square measures of association between categorical variables and contingency tables, and Spearman's Rank Order correlation between the ordinal variables.
Groups were compared using Wilcoxon rank sum tests for ordinal or continuous variables and contingency χ tests for categorical variables.
The Kruskal Wallis test was used to compare continuous variables, and contingency tables with the χ test were used for categorical variables.
Univariate comparison between the two cohorts (on HAART vs. not on HAART) was performed using the Wilcoxon rank-sum tests for continuous variables and contingency tables for categorical variables.
To perform the bivariate analyses, Mann-Whitney U tests were used for continuous variables and contingency tables for categorical variables (χ2 or Fisher's exact test if n≤5 per cell).
The differences in demographic and clinical characteristics between groups were calculated by comparison of means in quantitative variables, parametric or nonparametric according to the normal distribution of each variable, and contingency tables for qualitative variables, with a Yates correction when necessary.
Differences between groups were calculated by Student's t-test for continuous variables and by contingency tables for nominal variables.
Differences between groups were assessed by logistic fit for continuous variables and by contingency analysis for categorical variables.
The differences between the groups were assessed by logistic fit for continuous variables and by contingency analysis and specifically Pearson Chi-square tests, for categorical variables.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com