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The dependent variable was determined as the cumulative number of symptom episodes of a specific kind (skin, respiratory, etc).
Similarly, the stability of each variable was determined as the fraction of reduced models containing the variable; to take performance into account we defined an alternative variable stability score by summing the average time-dependent AUCROCs of the reduced models that include the variable.
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The relative and absolute frequency of categorical variables was determined, as well as the average and standard deviation of continuous variables.
An advantage is given to the two-factor descriptive model in that the status of a variable is determined as an outcome of the analysis and not by the investigator.
Variables were determined as pH, stirring speed and deposition time.
Regression analysis indicated that the optimal concentrations of these variables were determined as: glycerol 79.60 g/L, sodium glutamate 77.40 g/L, and skim milk 116.40 g/L.
Slack variables are determined as follows: xi = left| {y - f x,w)} right| - varepsilonquad {text{for data above an }},varepsilon text{text{tube}}, (11) xi^ = left| {y - f x,w)} right| - varepsilonquad {text{for data below an }} varepsilon text{text{tube}}.
Accordingly the optimum condition was set as: 2.0 mg HKUST-1-MOF-NA-MIP, 200 μL eluent and 5.0 min sonication time in center points other variables were determined as the best conditions to reach the maximum recovery of the analyte.
Using a 44 mm (id) reactor, the optimum values for these variables were determined as comprising a 2.3 nm thick iron catalyst layer on a silicon substrate with 50 nm of thermal oxide; 670 °C running temperature; 650 sccm helium and 34 sccm acetylene for 20 min.
Initial values for model variables were determined as follows.
Clinical and laboratory variables were determined as pharmacodynamic and safety criteria until 216 hours.
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