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We found evidence of positive selection with variable selective pressure among sites in the four groups of sequences analyzed (P < 0.01) (AVRK1-like full length, AVRK1-like truncated, AVRA10-like full length and AVRA10-like truncated).
Model M1a (nearly neutral), which hypothesizes a variable selective pressure among sites but not positive selection and M2a, which considers positive selection, fit our data better than the M0 model, with an ℓ = -6689.544 in both cases (Table 2).
The LRT comparing M3 with M0 is a test of variable selective pressure among sites whereas the other two LRTs are tests of positive selection among sites.
In order to detect variable selective pressures in the first exon of Catsper1 and infer residues under positive selection we applied models that account for heterogeneous ω ratios among amino acid sites [ 38].
For this purpose, the previously proposed variable selective control (VSC) methodology is extended to the nonlinear systems.
This paper presents a variable selective control methodology for control of networked systems subject to transfer delay, packet-loss and packet-disordering.
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Results showed that by week 14 there was more than 60% improvement in functional variables, selective improvement in clinimetric scores (for example chest expansion, P < 0.021), and significant improvement in inflammatory markers, which were maintained from week 6.
Variable rate selective excitation (VERSE) is a technique that modifies the original RF and gradient waveforms such that slice profile is unchanged.
The ratio of nonsynonymous to synonymous substitutions, dN/dS, which is a measure of variable Darwinian selective pressures, was estimated by maximum likelihood from the PEG11 coding sequence alignment using the codeml program from PAMLv4 [49].
The oligonucleotide sequences were designed inside the HCDR3 regions, since they represent the most variable (thus, selective, in terms of DNA sequence) regions in the antibody repertoire.
In their review, multiple immune disorders (i.e., common variable immunodeficiency, selective IgA deficiency, and specific antibody deficiencies) are discussed including appropriate diagnosis, treatment, and impact on CRS.
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