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However, subgroup analyses resulted in variable conclusions, indicating that the choice of measures for SCD meta-analyses can impact conclusions.
Eventually, the classical analysis of biomarker performance does not consider the evolving risk factors and changing treatments during IFD, which can lead to variable conclusions.
Other studies have evaluated overall expression of LC3 in cancer, with variable conclusions regarding significance.
Several previous meta-analyses [ 35– 38] have been performed, yielding variable conclusions, which may result from different methods and the underlying heterogeneity of exposure and health outcome data specificity and validity among published studies.
Given the variable conclusions reached in several investigations concerning sex chromosome dosage compensation in different organisms [ 38- 42], how confident can we be that any particular report has accurately measured expression levels clustered by a chromosome-to- chromosome level?
While the studies yielded variable conclusions, levels of circulating plasma OPN may be a biomarker of ovarian cancer [ 12], as there was a trend for decreased OPN levels following treatment of ovarian cancer, and levels rose early in patients with recurrent disease [ 13].
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None of the other independent variables (conclusion, product age or primary author's country) were significantly associated with the inclusion of any actual cost or any mention of costs.
This was recently discussed by Greve et al. [8] who showed that the use of different PVC methods resulted in variable study conclusions.
However, the sample size of the study was small and the behaviour changes of employees were very variable preventing conclusions from being drawn [ 9].
We have considered the most commonly used explanatory variables for inferior outcome and found that an interaction variable affected conclusions, and that as much as 25% of the explained variance could be attributed to the surgeon level.
Within each of these four fields, variables allowing conclusions of not only when they work, but also why, whether to test these variables during one occasion or many, questionnaire design, and field data analysis are considered.
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