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Few of the drinking water variables associated with risk from water consumption were significant in the single variable analysis (Table A1).
Patients with C. coli infection were more likely to describe their ethnicity as Asian and to have traveled abroad in the 2 weeks before the onset of symptoms (single-risk variable analysis; Table 2).
In the multivariable instrumental variable analysis (table 3), the use of proton pump inhibitors was associated with an increased absolute difference in risk of pneumonia of 8.2 (0.5 to 15.9) per 1000 patients compared with the use of H2 receptor antagonists, which corresponded to a number needed to harm of 122 (95% confidence interval 63 to 1946).
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In the first analysis, the serum potassium level was considered a continuous variable (analysis 1, Table 2).
Categorical scores for the individual radiographic features were converted to binary variables for analysis (Table 1).
For postsurvey variables, univariate analysis (Table 4) also showed a statistically significant association between MDR rates and retreatment failure rates.
The accuracy of this nomogram was 78% and outperformed any other variable on univariate analysis (Table 2).
Four factors namely molar ratio (X1), catalyst concentration (X2), reaction time (X3) and reaction temperature (X4) were considered as variables for this analysis (Table 3).
DFS and OS were analysed as a function of the different variables in univariate analysis (Table 3-wrap>).
The multivariate analysis confirmed the association between colonocopic surveillance and improved survival, but failed to reach statistical significance most probably because of a type II error resulting from multiple variables in the analysis (Table 2).
Age, serum PSA, DRE and body mass index (BMI), statins, aspirin, and the combination between statins and aspirin treatments as well as the duration of those were included as predictive variables in this analysis (Table 3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com