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Previous studies based on IHC demonstrated variable alterations in up to 73% of cases [ 8- 10, 27].
In addition to demonstrating alterations in chemoattractant receptor expression, dynamic and variable alterations in neutrophil chemoattractant receptors in vivo correlate with changes in cell function (chemotaxis).
The size of the CNA at 2p has been reported to vary from case to case and from cell to cell, indicating that 2p is indeed prone to variable alterations.
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Its thickness varies between 300 and 2000 m with a variable alteration zone (from 420 to 970 m).
Using a device designed to produce variable alteration of infarct stiffness and geometry, we sought to understand how these parameters affect LV function and remodeling early after MI.
Congenital adrenal hyperplasia is the commonest cause of 46,XX DSD with ambiguous genitalia in the neonatal period or early infancy and is characterized by androgen excess and a variable alteration in glucocorticoid and mineralocorticoid function and a specific profile of steroid hormones.
These findings indicate that the selection of an AUG codon depends on numerous variables, alteration of which can redirect translation initiation.
Out of four primary variables, weakness and motor coordination showed a statistically significant difference between alcohol and non-alcohol group, out of 14 secondary variables, five more variables (dizziness, alterations in sight, alterations in walking, agitation and alterations in speech) also showed significant differences due mainly to contrasts with the non-alcohol group.
Because of the existence of very variable genetic alterations in different ethnic communities, none of the assays developed for screening mutations/deletions in a population defined can be adapted to study the possible genetic defects.
As progress of dysplastic hepatocytes to HCC might occur simultaneously in different foci or nodules, variable genomic alterations can be found within the same liver indicating a genetic heterogeneity of lesions (Feitelson et al, 2002).
For those response variables showing alterations with U-tAs or LAsE concentrations in the first set of analyses, we further present the findings with the exposure variable stratified to further explore exposure response relationships.
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