To find out whether a tumor genome shows a significant difference in repeat incidence or variability to a normal genome, it is necessary to compare (i) the incidence or variability of repeats in a tumor genome relative to its matched normal genome to (ii) the incidence or variability of repeats between two normal genomes.
In fact, as a measure of brain activity, FDG PET is susceptible to biological variability due to normal aging, current state of arousal level, local inflammation, and other non-neuronal sources of metabolic changes, possibly resulting in misdiagnosis [ 10, 13, 14].
We have extensive experience with this issue, and have found this level of variability to be quite normal when comparing between different strains of fish or across biological repeats.
Therefore, the variability of dose to normal liver within the organ can be characterized more specific than in the classical partition model.
This is in agreement with our results showing that MMP-7, -8 and TIMP-1 though its' variability can return to normal levels within 6 months after the patients successfully quits smoking.
Slight differences in the initial burst intensity between the 1 g and the rotated treatment were due to normal variability of different cell batches.
First, it is a high cut-off value, which excludes potential changes of LS due to normal variability in measures between examinations.
It is possible that previous genomics studies of human osteosarcoma failed to capture the true biological variability between individuals due to normal sample pooling.
This nonvalidated cut-point was chosen in order to differentiate between responsive and nonresponsive patients as fluctuations in these values of greater than 10% would be less likely to occur due to normal variability alone.
Unfortunately, the reliability and sensitivity of this walk test are not well defined and, therefore, limit our ability to evaluate real changes in gait speed not attributable to normal variability.
