All statistical analyses were conducted using STATA/MP V.12.1 (StataCorp, College Station, Texas, USA) and multilevel models were fitted using STATA survey commands to adjust for the variability of clustering.
The ICC-adjusted test statistic is generally recommended to effectively control the nominal level when there is constant or small variability of cluster sizes.
Of note that (at least) two sources of variability of cluster memberships need to be scrutinized as follows: variability due to the stochastic nature of the Monte Carlo clustering method and variability due to different parts of an MD trajectory being clustered.
To answer this question, we shall quantify the variability of clusters for subsets, relate it to the result for the whole trajectory, and derive a "stiff kernel," that is, those atoms which do not (or very rarely) change clusters between subsets of the trajectory.
Indeed, the K-means cluster analysis is exploratory in nature, and the scale and variability of the clustering variables may affect results in unstandardised analyses [ 74].
That is, in case the same set of axes are relevant to the explanation of the variability of all clusters (high within-axes heterogeneity), non-centered PCA results in a single generic component [43].
p. 685, 2001), based on the memorization and recursive update of a small number of summary statistics, but they either don't take into account the specific variability of the clusters, or assume that the random vectors which are processed and grouped have uncorrelated components.
All these results are in agreement with the reported interindividual variability of DEF cluster b genes [ 20].
3) PA T6SS-3 Companalysisanalysis of PA T6SS-3 showed that there was no variability of this cluster between the different strains of P. ananatis.
The intra and inter session variability of the Cluster method is lower than that of the Traditional method especially for overweight and obese subjects.
