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In order to compare the effect of insulin aspart vs insulin lispro on daytime glucose stability, in patients with Type 1 diabetes mellitus during a CSII treatments, we designed a randomised, cross-over group trial of aspart vs lispro on daytime glycaemic variability evaluated with Continuous Glucose Monitoring System (CGMS).
The interindividual variability, evaluated with samples from five subjects, was 9.2% at 500 pM.
The two quantification methods were confronted and the interobserver variability evaluated.
In the present study, inter-individual pharmacokinetic variability (evaluated as the coefficient of variation of the pharmacokinetic parameters) was 10%and30%0% (average 20%).
Intraspecific variability evaluated based on the detection of 2629 DArT markers was found to be higher in both ryegrass species as compared to the fescues.
The fruit texture variability evaluated within the apple collection over two years of observation is illustrated by the PCA plot (Additional file 3).
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While stride time variability evaluates consistency of the loading response, as reflected in the variability in the time between consecutive heel-strikes, swing time variability reflects the stride-to-stride consistency of both the loading and unloading of body weight.
We conducted a six-year analysis of more than 66,000 individual patient admissions to 24 ICUs across Australia and New Zealand to: describe the incidence of and clinical factors associated with early hypoglycemia and BG variability; evaluate the association between early hypoglycemia, BG variability and mortality; and explore the association between severity of early hypoglycemia and mortality.
The intra- and inter-variabilities evaluated for KL grade (0-4) were confirmed by kappa analysis to be sufficient for assessment (0.86 and 0.80, respectively).
Inter-operator variability The inter-operator variability was evaluated for three of the patient SPECT images.
In addition to the data from the calibration scans, radionuclide activity meter variability was assessed using data from daily constancy tests, and camera variability was evaluated using count rates from daily extrinsic flood quality control acquisitions.
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