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PLGA/gelatin electrospun scaffolds also showed higher values of these markers than TCPS.
Although the values of these markers often evolve over time, no study has examined the accumulated effects of these abnormalities on important clinical end points.
By selecting and isolating, from the initial population, a subpopulation with similar values of these markers, it turns out that the initial wide distribution is eventually restored.
(3) How can changes in the values of these markers be interpreted?
The predictive values of these markers for disease severity and organ dysfunction were also investigated.
It should be noted that the low mean baseline values of these markers make clinical interpretations difficult.
Similar(47)
The q-value of these markers varied between 0.01 and 0.16 (Table 3), which can be deemed reasonable and justifies the chosen threshold.
For instance, the group used a genome-wide epigenetic screen to identify novel methylation markers for melanoma and is now using patient samples to assess the prognostic value of these markers.
Results of this trial should provide both an idea of the activity of neoadjuvant pemetrexed in breast cancer and information on biomarker association with clinical performance that can be used in the design of additional clinical studies to assess the predictive value of these markers.
As a first step, however, confirmation of the diagnostic value of these markers in a controlled study in independent clinical centers, different from the ones that were involved in the identification of the biomarkers, has to be obtained.
However, this question will not be solved until the predictive value of these markers is proved in a series of patients with different evolutive status and secondly until the consistency of the results in different muscles and different laboratories is proved.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com