Exact(7)
The values of substitution frequencies in quasispecies were clustered as either more than 80% or less than 20%, forming a unique U-shaped distribution pattern in both clinical groups.
Simulations for 100, 200 and 300 years (with the baseline values of substitution rates and other parameters) made it possible to analyze the trade-offs between harvested volume and carbon balance (Fig. 7).
Except for SVP, the median values of substitution scores in the core regions of proteins are always smaller than those from the surface regions.
In addition, the average proportions of variants having negative values of substitution score are 63% and 55% for SVD and CSM respectively, whereas the average proportions are less than 40% for SVP and SAP (see Table S1).
Median values of substitution rates of each species and p-values.
Comparison of decay values of substitution data versus substitutions plus SIC-coded indels showed higher decay values for most nodes when indel information was included (see Additional file 2, Figure S1).
Similar(53)
The highest values of substitutions, either synonymous or non-synonymous, and the highest virus diversity, evaluated by genetic distance, were found in patients with sustained virological responses (SVR).
Tajima's D statistic is calculated as D = (π - θs)/[Var(π - θs]1/2 The value of D is expected to be zero for selectively neutral variants in a constant population. A non-zero D value is a sign of departure from the neutral model caused by a relative excess (positive D values) or deficiency (negative D values) of substitutions of various frequencies [ 54].
The reduced value of substitution energy indicates that substitution of Pb with indium becomes less favorable with the increased In doping concentration.
A substitution rate (SR) function for a model ℳ is a non-negative continuous function Δ : ℳ → R + that maps each transition matrix onto a numerical value of "substitution rate".
The median values of the substitution scores were then calculated and stored as a pairwise distance matrix.
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