Sentence examples for values of linkage from inspiring English sources

In the absence of recombination, linkage disequilibrium measures tend to reflect the shape of the tree (the tendency of mutations to appear on related branches [52]) and maximal absolute values of linkage disequilibrium tend to decrease with decreasing frequencies of the mutations.

In fact, the 1,403 comparisons of nuclear vs. mitochondrial sites yielded 772 significant values of linkage disequilibrium (see Additional File 1, Table S1).

The boxes painted in black indicate values of linkage disequilibrium that are highly significant, present mainly in the superior portion of the graph, which represents the complete set of 485 accessions (thematic collection).

The program Powermarker was also used to estimate linkage disequilibrium between the microsatellite loci, through the coefficients D' [ 27] and r 2 [ 28] and also to estimate the significance of the values of linkage disequilibrium between pairs of loci.

There was a change in the scenario when the analysis was performed with the 87 accessions that compose CC corex, with only 24% of the possible comparisons presenting significant values of linkage disequilibrium.

The Hardy-Weinberg equilibrium (HWE) was verified for all the investigated polymorphisms using the exact test proposed by Wigginton et al. 33 The HaploView 4.2 genetic software package 34 was used to estimate values of linkage disequilibrium (LD) coefficient r as well as to estimate haplotype frequency and to compare it among the study groups.

The R2 value of linkage disequilibrium was calculated for all possible marker pairs within each chromosome.

To detect the small-effect QTL, the threshold value of linkage was set as P = 0.05 (Chi-square test).

To identify these potential small-effect QTL, we reanalyzed the data using a lower threshold value of linkage (P = 0.05).

Most of these genomic regions did not reach a genome-wide significant threshold value of linkage, with P values between 0.05 and 0.001 [ 1- 5].

This suggests that there must be other susceptibility genes whose contributions were not big enough to reach the stringent significance threshold value of linkage analysis.