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Following partial sleep deprivation, mean daytime values of leptin were approximately 18% lower compared to the rested state.
Values of leptin in both groups were lower in cord than in maternal serum, and those of RBP4 were lower in only GDM women.
94 In a large cohort study of 1,024 subjects, shorter habitual sleep duration as assessed by sleep diaries related to lower morning values of leptin.
Average values of leptin and adiponectin in carriers of various genotypes of the leptin and leptin receptor genes were not different.
Presence of diabetic status, irrespective of BMI itself indicates breast cancer risk in the studied subjects owing to above or below the normal cutoff values of leptin and adiponectin levels respectively.
Median values of FBG, insulin, and HOMA-IR were significantly higher in Down versus non Down groups, while median values of leptin and leptin resistance were non-significantly different among Down versus non Down groups.
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Hence, the value of leptin as a marker of risk remains unclear in CKD.
Figure S1 Mean value of Leptin levels of male and female subjects in different diagnostic groups.
Considering leptin and leptin-R, a higher median value of leptin in OD children was observed in this study, however, no significant difference in leptin and leptin -R were observed between OD versus OND, indicating an increase in median leptin values, a marker of leptin resistance in obese children irrespective to the cause of obesity.
The predictive value of leptin seems weaker than that of adiponectin, because we found no association of baseline leptin level and structural damage at inclusion of RA patients or subsequent rapid disease progression (∆SHS ≥5).
Thus, the objective of the present study was to assess the association of leptin with metabolic syndrome and CVD risk in Taiwanese adults as well as the predictive value of leptin levels for identifying patients with metabolic syndrome.
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