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Specifically, the number of expressed genes (Y axis), depending on the sequencing depth f (X axis), for different values of a threshold parameter is presented in Fig. 4.
Finally, EPI is a "smoothed" version of GPI, obtained by averaging a slightly modified form of GPI over all possible values of a threshold for statistically significant differential gene expressions.
26 We evaluated a linear threshold model repeatedly for a wide range of possible values of a threshold dose (d0), modelling the risk function ERR on doses d as β(d−d0) for d>d0 or d=0 for d≤d0.
The results for a TNBC-free patient (SRR1313211) and a TNBC patient (SRR1313133), exemplary for all samples studied, are shown in Fig. 5; the number of expressed genes (Y axis), depending on the sequencing depth f (X axis) for different values of a threshold parameter ⊝ϵ{1, 10, 50, 100}, are also presented.
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The model optimizes the maximum likelihood value of a threshold, such that the nodes before the threshold are identified as species diversification events, while the branches beyond the threshold are clusters following coalescent processes.
The individual-level and the population-level approaches may produce very different numbers as the first calculates the value of R0, whilst the second calculates the value of a threshold parameter.
For low values of ΔT, a threshold can de defined depending on the R ratio.
For the significance test of the mutual information values we obtain a threshold value of 0.414.
Values of VEI above a threshold value of 20 ml/kg (1.4 L in an average adult) have been shown to predict complications of hypotension and barotrauma [ 68].
This suppresses possible signal that falls between the value of a symmetric threshold and Ek in a given tumor.
In addition, the predictive value of a PPV threshold of 13% was also evaluated.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com