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Growth inhibition assays were carried out and the GI50 values for each agent was determined as described previously.
The observed T/C values in the combination group were smaller than calculated T/C values based on the T/C values for each agent alone, confirming a synergistic interaction (Table 1).
The obvious step to a more realistic model is to treat (alpha ) and (sigma ) as having different values for different agents (i.e. as agents' attributes).
Both the vagueness of prior plausibility ratio values for individual agents and the diversity of values among the community of agents can be represented formally by sets of probabilistic support functions, {Pα, Pβ, …}, that agree on the values for the likelihoods but encompass a range of values for the (ratios of) prior probabilities of hypotheses.
They were sensitive to most of the antimicrobial agents tested, except for tetracycline, sulfamethoxazole, trimethoprim, and trimethoprim-sulfamethoxazole; MIC values for these agents were similar (Table).
The optimum values for biostimulation agents to achieve a predicted maximum TPH and Cr (VI) removal of 67.20% and 53.20%, respectively, were found to be as follows: NPK fertilizer, 4.22 g; Tween 80, 10.69 mg/l; and pig manure, 47.76 g.
A summary of the MF values for these agents is presented in Table I.
Similarly, LC50 values for single-agent mithramycin were 0.3 μM for BXPC-3 and 0.2 μM for MIAPaCa2 cells.
LC50 values for single-agent mitoxantrone were approximately 10 μM for PC3-TR and PC3 cells, and 5 μM for Panc-1 cells.
The LC50 values for single-agent mithramycin were 20 μM, 0.5 μM and 6 μM for PC3-TR, PC3, and Panc-1 respectively.
In contrast, the EC50 values for these agents in MCF-10A cells were much greater than 20 μM even after a 24 h incubation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com