The standard curve was produced by measuring the crossing point of each standard value (twofold serially diluted cDNAs from the Human Universal Reference Total RNAs) and plotting them against the logarithmic value of the concentration.
In contrast, the ability of TAK-779 to inhibit chemotaxis was hardly changed by mutation of the same five CXCR3 residues, with the H202A and Y308A7.43 mutations apparently increasing the IC50 values twofold when compared with WT CXCR3.
Results highlighted in blue represent statistically significant values (P ≤ 0.05), and results highlighted in bold and blue represent statistically significant values with differential values near twofold or above.
The threshold value was determined from the mean value plus twofold SD from the healthy group.
"We look at the value as twofold," Mr. Tisch said.
The region's strategic value is twofold: it links Damascus with the Mediterranean coastal enclave that is the heartland of Assad's Alawite sect; and rebels smuggle weapons and supplies from Lebanon across the porous frontier to opposition fighters in Syria.
For managers like Riemer, the test's value is twofold.
As marketing dollars shift towards social media and content marketing (according to Custom Content Council, 68percentt of CMOs are shifting marketing budgets to focus on content marketing), and simultaneously, as digital content production ushers in a new era where many bloggers and journalists are now managing freelance careers, Contently's value is twofold.
Total dimensional continual flux (k, n ∈N) of the unit hyperspherical function HS k,n,1) is equal to the value of twofold integral ∫ 0 ∞ ∫ 0 ∞ 2 π k r k + n - 3 Γ ( k ) Γ ( k + n - 2 ) Γ k 2 d k d n, (3.1).
Values above twofold (black dashed line) are significant (p<0.05).
Red and blue closed squares represent differentially expressed genes at 0.05 FDR corrected p-values and twofold change in expression.
