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As such, we consider it of considerable value to inform the health-care professionals of those aspects that are susceptible to modification based on the information received from their outpatient clinics.
For this purpose the discrimination and reliability of the dimension sub-scales would be of interest: if the sub-scales are unreliable or fail to discriminate between patients then they will be of doubtful value to inform focused interventions.
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Giere (2003) replies that what counts as socially progressive will vary among philosophers, and that in a democracy, it is unlikely that a unanimous or near unanimous consensus regarding the values to inform philosophical analysis or scientific inquiry could be achieved either in the larger society or in the smaller social subset of philosophers of science.
Other ways of valuing health gains in UK government departments, such as "statistical life" values to inform decisions on transport safety, or willingness to pay for improved air quality, also give values per year of life in the range £27 500-£27 000.
Because of this, several SNV detection methods consider forward reads and reverse reads separately, using some combination of the two obtained p-values to inform the final SNV calling decision [ 18, 25].
In this paper we describe recruitment and participation in the pilot panel study and discuss the potential for extension of this approach to fulfil the need for eliciting utilities from the general public for research purposes and to support the need for these values to inform allocation policy decisions.
In their 2009 guidance, NICE describe three types of potential selection bias or uncertainty to consider: Structural uncertainty (categorisation of different states of health and the representation of different pathways of care); source of values to inform parameter and parameter precision (uncertainty around the mean health and cost inputs in the model).
Our two aims were to establish whether there are combinations of symptoms and signs for which nerve conduction studies are very unlikely to be abnormal and therefore are of dubious value, and to inform choices of case definition for use in epidemiological studies.
Models are only as useful as the data available and parameter values estimated to inform them.
Our results highlight the advantages of using systems-level strategies to add value to and inform GWAS.
The final set of analyses will present estimates of the global and partial value of perfect information, to inform future research.
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