Despite the relatively narrow range of binding affinities (Ki values) reliable statistical models with good predictive power have been obtained.
A total of 200 data sets were generated in accordance to recent guidelines [ 6, 16] in order to make both estimates, confidence intervals and p values reliable.
The aforementioned data show that the obtained AUC5−t values are reliable values, which we can use for comparative pharmacokinetics.
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This proves that the estimated value is reliable.
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However, the reference value is reliable because the ordinary spinner magnetometer is routinely cross-calibrated using several calibration specimens.
