This assessment indicated an awareness of these management issues among stakeholders, but revealed that overall, these stakeholders place more value on outcomes than the administrative and management processes required to achieve those outcomes.
Finally, Scenarios S13 and S14 considered a sensitivity analysis for toxicity parameter values on outcome metrics.
In all adjusted analyses we performed sensitivity analyses to check for the effect of missing values on outcome by adding an extra category with missing values.
Children with non-missing values on outcome variables and key predictors were kept in the analysis, yielding a total sample of 1,231 children with 2,555 observations.
For variables with a skewed distribution (>0.3), medians and interquartile ranges were reported, with Mann Whitney U tests used to compare median values on outcome measures between groups.
Further, patients who seek the best treatment for their conditions might value information on outcome scores of health care providers.
To the best of our knowledge, there are few studies exploring the effectiveness of treatment based on PiCCO-derived physiological values on outcomes of patients with severe thoracic trauma and ARDS.
In addition, patients may have different expectations about treatments and place different values on outcomes from those of health-care professionals (Meropol et al, 2008).
Its predictive value on disease outcome, including both articular and cardiovascular issues, will have to be evaluated in upcoming prospective studies.
The other approach, often referred to as the "residual change score" approach, involves having the follow-up value on the outcome of interest predicted by the baseline value, as well as other risk factors (or covariates).
