Sentence examples for value of the variant from inspiring English sources

For the second study assessing the prognostic value of the variant alleles in SS group, given the frequency of the variant genotype, and an expecting mortality rate at 35 40 % in the SS subgroup group, we considered that 870 SS patients were sufficient for a power at 0.90 (type I error at 0.05) to identify a 30%% difference in genotype frequency.

The significant increase in the KM value of the variant E210A (382 μM) compared to the wild-type enzyme reflects a more than 5-fold decrease in chlorite binding at the distal heme cavity.

The Km value of the variants toward H2O2 was increased, but Km value toward 2,4-DCP degradation was reduced.

We calculated the area under the precision-recall curve (AUPRC) as well, using trapezoid rule integration [ 40], and we calculated the differences between the AUPRC values of the variant callers and VariantMetaCaller.

During the voting process, if an impasse occurs the QoS values of the variants are used to select one response.

The T 50 value of the CYP102A1.1 reductase domain was 45°C and the T 50 values of the variants' reductase domains were in the range of 40-48°C 40-48°C

In contrast to the wild-type pro-TGase, all of the variants had decreased specific activities, and both the Km and kcat values of the variants decreased accordingly.

Although the Km values of the variants decreased, their kcat values also decreased accordingly compared with the wild-type enzyme (Table  1).

The KM values of the variants are not markedly different from that of the wild type, except for those of BsDHFR-A104Q and BsDHFR-L20M/A104Q, which show KM values for NADPH 5-fold lower than for the wild type.

In this work, we investigated the biological and clinical significance of the SNP KIT L541 in GIST patients, its potential role in carcinogenesis and the potential predictive value of this variant for GIST patients outcome.

Future experiments involving a larger MMD patient population will further define the clinical diagnostic value of the ZXDC variant.